English name: Isoquinoline
CAS Number: 119-65-3
Formula: C9H7N
molecular weight: 129.16
Content: 98%
Properties:
Colorless flake crystals or liquid. The melting point of 26.48 ° C, the boiling point of 242.2 ° C (99.1kPa), the relative density of 1.09101 (30 / 4 ° C), the refractive index of 1.62078 (30 ° C), a flash point of 107 ° C. It is miscible with many organic solvents and soluble in dilute acid. It is water-absorbing and alkaline is stronger than quinoline. It has a smell similar to fennel oil and anisole. Can volatilize with water vapor. After storage, the color is yellow. pKa = 5.4, slightly more basic than quinoline, can form salts with various acids: its hydrochloride salt melting point 209 ° C, picrate melting point 223 ° C. The acylation and alkylation reaction can occur on N, and the methyl iodide has a melting point of 159 °C. Electrophilic substitution occurs at the 5 or 8 position. The nucleophilic substitution occurs in the 1st position. Oxidation and reduction reactions are apt to occur. It is present in coal tar and can be prepared by the reaction of Schiller-Napierelsky or the Pomeranz-Fric reaction. Some important alkaloids contain isoquinoline rings.
Uses:
It can produce drugs and high-efficiency insecticides. It can be made into pyridine carboxylic acid after oxidation. Its derivatives can be used to make color films and dyes. Used as an intermediate in synthetic drugs, dyes, insecticides and gas chromatographic fixatives.
Packaging, storage and transportation: